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1

Structural basis for recognition of diverse antidepressants by the human serotonin transporter

Coleman, Jonathan A., Gouaux, Eric

Journal:

Nature Structural and Molecular Biology

Year:

2018

Language:

english

File:

PDF, 1.76 MB

english, 2018

2

Gating mechanisms of acid-sensing ion channels

Yoder, Nate, Yoshioka, Craig, Gouaux, Eric

Journal:

Year:

2018

Language:

english

File:

PDF, 9.06 MB

english, 2018

3

10.1038/45568

Gouaux, Eric, Chen, Guo-Qiang, Cui, Changhai, Mayer, Mark L.

Journal:

Year:

1999

Language:

english

File:

PDF, 725 KB

english, 1999

4

X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor

Sobolevsky, Alexander I., Rosconi, Michael P., Gouaux, Eric

Journal:

Year:

2009

Language:

english

File:

PDF, 2.99 MB

english, 2009

5

X-ray structures and mechanism of the human serotonin transporter

Coleman, Jonathan A., Green, Evan M., Gouaux, Eric

Journal:

Year:

2016

Language:

english

File:

PDF, 9.25 MB

english, 2016

6

Mechanism of NMDA receptor channel block by MK-801 and memantine

Song, Xianqiang, Jensen, Morten Ø., Jogini, Vishwanath, Stein, Richard A., Lee, Chia-Hsueh, Mchaourab, Hassane S., Shaw, David E., Gouaux, Eric

Journal:

Year:

2018

Language:

english

File:

PDF, 7.20 MB

english, 2018

7

Cryo-EM structure of the benzodiazepine-sensitive α1β1γ2S tri-heteromeric GABAA receptor in complex with GABA

Phulera, Swastik, Zhu, Hongtao, Yu, Jie, Claxton, Derek P, Yoder, Nate, Yoshioka, Craig, Gouaux, Eric

Journal:

Year:

2018

Language:

english

File:

PDF, 5.94 MB

english, 2018

8

Mechanisms for Zinc and Proton Inhibition of the GluN1/GluN2A NMDA Receptor

Jalali-Yazdi, Farzad, Chowdhury, Sandipan, Yoshioka, Craig, Gouaux, Eric

Journal:

Year:

2018

Language:

english

File:

PDF, 12.57 MB

english, 2018

9

Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport

Coleman, Jonathan A., Yang, Dongxue, Zhao, Zhiyu, Wen, Po-Chao, Yoshioka, Craig, Tajkhorshid, Emad, Gouaux, Eric

Journal:

Year:

2019

Language:

english

File:

PDF, 15.14 MB

english, 2019

10

High Level Production, Characterization and Construct Optimization of the Ionotropic Glutamate Receptor Ligand Binding Core

Guo Qiang Chen, Eric Gouaux

Journal:

Year:

2000

Language:

english

File:

PDF, 780 KB

english, 2000

11

Overexpression of bacterio-opsin in Escherichia coli as a water-soluble fusion to maltose binding protein: Efficient regeneration of the fusion protein and selective cleavage with trypsin

Guo-Qiang Chen, J. Eric Gouaux

Journal:

Protein Science

Year:

1996

Language:

english

File:

PDF, 3.03 MB

english, 1996

12

α-Hemolysin, γ-hemolysin, and leukocidin from Staphylococcus aureus: Distant in sequence but similar in structure

Eric Gouaux, Michael Hobaugh, Langzhou Song

Journal:

Protein Science

Year:

1997

Language:

english

File:

PDF, 6.45 MB

english, 1997

13

Probing the ligand binding domain of the GluR2 receptor by proteolysis and deletion mutagenesis defines domain boundaries and yields a crystallizable construct

Guo-Qiang Chen, Yu Sun, Rongsheng Jin, Eric Gouaux

Journal:

Protein Science

Year:

1998

Language:

english

File:

PDF, 3.27 MB

english, 1998

14

Crystal structure of CTP-ligated T state aspartate transcarbamoylase at 2.5 Å resolution: Implications for ATCase mutants and the mechanism of negative cooperativity

Richard P. Kosman, J. Eric Gouaux, William N. Lipscomb

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1993

Language:

english

File:

PDF, 2.44 MB

english, 1993

15

The New York Consortium on Membrane Protein Structure (NYCOMPS): a high-throughput platform for structural genomics of integral membrane proteins

James Love, Filippo Mancia, Lawrence Shapiro, Marco Punta, Burkhard Rost, Mark Girvin, Da-Neng Wang, Ming Zhou, John F. Hunt, Thomas Szyperski, Eric Gouaux, Roderick MacKinnon, Ann McDermott, Barry Ho

Journal:

Journal of Structural and Functional Genomics

Year:

2010

Language:

english

File:

PDF, 385 KB

english, 2010

16

Structure-based functional design of chemical ligands for AMPA-subtype glutamate receptors

Lei Zeng, Luying Lu, Michaela Muller, Eric Gouaux, Ming-Ming Zhou

Journal:

Journal of Molecular Neuroscience

Year:

2002

Language:

english

File:

PDF, 75 KB

english, 2002

17

10.1038/27692

Gouaux, Eric, Armstrong, Neali, Sun, Yu, Chen, Guo-Qiang

Journal:

Year:

1998

Language:

english

File:

PDF, 915 KB

english, 1998

18

Roll out the barrel

Journal:

Natural Structural Biology

Year:

1998

Language:

english

File:

PDF, 347 KB

english, 1998

19

Mechanism of glutamate receptor desensitization

Sun, Yu, Olson, Rich, Horning, Michelle, Armstrong, Neali, Mayer, Mark, Gouaux, Eric

Journal:

Year:

2002

Language:

english

File:

PDF, 1.11 MB

english, 2002

20

10.1038/5821

Gouaux, Eric, Olson, Rich, Nariya, Hirofumi, Yokota, Kenji, Kamio, Yoshiyuki

Journal:

Natural Structural Biology

Year:

1999

Language:

english

File:

PDF, 630 KB

english, 1999

21

Crystal structure and association behaviour of the GluR2 amino-terminal domain

Jin, Rongsheng, Singh, Satinder K, Gu, Shenyan, Furukawa, Hiroyasu, Sobolevsky, Alexander I, Zhou, Jie, Jin, Yan, Gouaux, Eric

Journal:

The EMBO Journal

Year:

2009

Language:

english

File:

PDF, 1.90 MB

english, 2009

22

Structural basis for modulation and agonist specificity of HCN pacemaker channels

Zagotta, William N., Olivier, Nelson B., Black, Kevin D., Young, Edgar C., Olson, Rich, Gouaux, Eric

Journal:

Year:

2003

Language:

english

File:

PDF, 595 KB

english, 2003

23

Structure of a glutamate transporter homologue from Pyrococcus horikoshii

Yernool, Dinesh, Boudker, Olga, Jin, Yan, Gouaux, Eric

Journal:

Year:

2004

Language:

english

File:

PDF, 810 KB

english, 2004

24

Crystal structure of a bacterial homologue of Na+/Cl--dependent neurotransmitter transporters

Yamashita, Atsuko, Singh, Satinder K., Kawate, Toshimitsu, Jin, Yan, Gouaux, Eric

Journal:

Year:

2005

Language:

english

File:

PDF, 1.00 MB

english, 2005

25

Subunit arrangement and function in NMDA receptors

Furukawa, Hiroyasu, Singh, Satinder K, Mancusso, Romina, Gouaux, Eric

Journal:

Year:

2005

Language:

english

File:

PDF, 1.24 MB

english, 2005

26

Coupling substrate and ion binding to extracellular gate of a sodium-dependent aspartate transporter

Boudker, Olga, Ryan, Renae M., Yernool, Dinesh, Shimamoto, Keiko, Gouaux, Eric

Journal:

Year:

2007

Language:

english

File:

PDF, 912 KB

english, 2007

27

Antidepressant binding site in a bacterial homologue of neurotransmitter transporters

Singh, Satinder K., Yamashita, Atsuko, Gouaux, Eric

Journal:

Year:

2007

Language:

english

File:

PDF, 964 KB

english, 2007

28

Structure of acid-sensing ion channel 1 at 1.9 Å resolution and low pH

Jasti, Jayasankar, Furukawa, Hiroyasu, Gonzales, Eric B., Gouaux, Eric

Journal:

Year:

2007

Language:

english

File:

PDF, 1.69 MB

english, 2007

29

Unlocking the molecular secrets of sodium-coupled transporters

Krishnamurthy, Harini, Piscitelli, Chayne L., Gouaux, Eric

Journal:

Year:

2009

Language:

english

File:

PDF, 2.96 MB

english, 2009

30

Crystal structure of the ATP-gated P2X4 ion channel in the closed state

Kawate, Toshimitsu, Michel, Jennifer Carlisle, Birdsong, William T., Gouaux, Eric

Journal:

Year:

2009

Language:

english

File:

PDF, 1.72 MB

english, 2009

31

Neurotransmitter/sodium symporter orthologue LeuT has a single high-affinity substrate site

Piscitelli, Chayne L., Krishnamurthy, Harini, Gouaux, Eric

Journal:

Year:

2010

Language:

english

File:

PDF, 343 KB

english, 2010

32

Principles of activation and permeation in an anion-selective Cys-loop receptor

Hibbs, Ryan E., Gouaux, Eric

Journal:

Year:

2011

Language:

english

File:

PDF, 1.81 MB

english, 2011

33

Structural basis for partial agonist action at ionotropic glutamate receptors

Jin, Rongsheng, Banke, Tue G, Mayer, Mark L, Traynelis, Stephen F, Gouaux, Eric

Journal:

Nature Neuroscience

Year:

2003

Language:

english

File:

PDF, 2.17 MB

english, 2003

34

Structure and function of AMPA receptors

Journal:

The Journal of Physiology

Year:

2004

Language:

english

File:

PDF, 251 KB

english, 2004

35

Molecular mechanism of ATP binding and ion channel activation in P2X receptors

Hattori, Motoyuki, Gouaux, Eric

Journal:

Year:

2012

Language:

english

File:

PDF, 2.08 MB

english, 2012

36

A new protein folding screen: Application to the ligand binding domains of a glutamate and kainate receptor and to lysozyme and carbonic anhydrase

Neali Armstrong, Alexandre De Lencastre, Eric Gouaux

Journal:

Protein Science

Year:

1999

Language:

english

File:

PDF, 643 KB

english, 1999

37

Structural plasticity and dynamic selectivity of acid-sensing ion channel–spider toxin complexes

Baconguis, Isabelle, Gouaux, Eric

Journal:

Year:

2012

Language:

english

File:

PDF, 1.82 MB

english, 2012

38

Membrane proteins — pumping along

Stephen H White, J Eric Gouaux

Journal:

Current Opinion in Structural Biology

Year:

2005

Language:

english

File:

PDF, 71 KB

english, 2005

39

Membrane proteins — pumping along [Current Opinion in Structural Biology 2005, 15:375–377]

Stephen H White, J Eric Gouaux

Journal:

Current Opinion in Structural Biology

Year:

2006

Language:

english

File:

PDF, 48 KB

english, 2006

40

Fluorescence-Detection Size-Exclusion Chromatography for Precrystallization Screening of Integral Membrane Proteins

Toshimitsu Kawate, Eric Gouaux

Journal:

Year:

2006

Language:

english

File:

PDF, 481 KB

english, 2006

41

Lipids lost, lipids regained

Eric Gouaux, Stephen H. White

Journal:

Current Opinion in Structural Biology

Year:

2001

Language:

english

File:

PDF, 48 KB

english, 2001

42

Membranes: Proteins and membranes – a fusion of new ideas

Eric Gouaux, Stephen H White

Journal:

Current Opinion in Structural Biology

Year:

2003

Language:

english

File:

PDF, 55 KB

english, 2003

43

Membrane proteins

Werner Kühlbrandt, Eric Gouaux

Journal:

Current Opinion in Structural Biology

Year:

1999

Language:

english

File:

PDF, 331 KB

english, 1999

44

The long and short of colicin action: the molecular basis for the biological activity of channel-forming colicins

Journal:

Year:

1997

Language:

english

File:

PDF, 283 KB

english, 1997

45

It's not just a phase: crystallization and X-ray structure determination of bacteriorhodopsin in lipidic cubic phases

Journal:

Year:

1998

Language:

english

File:

PDF, 232 KB

english, 1998

46

Single potassium ion seeks open channel for transmembrane travels: tales from the KcsA structure

Journal:

Year:

1998

Language:

english

File:

PDF, 600 KB

english, 1998

47

Mechanisms for ligand binding to GluR0 ion channels: crystal structures of the glutamate and serine complexes and a closed apo state

Mark L Mayer, Rich Olson, Eric Gouaux

Journal:

Journal of Molecular Biology

Year:

2001

Language:

english

File:

PDF, 1.28 MB

english, 2001

48

α-Hemolysin fromStaphylococcus aureus:An Archetype of β-Barrel, Channel-Forming Toxins

Journal:

Journal of Structural Biology

Year:

1998

Language:

english

File:

PDF, 1.74 MB

english, 1998

49

The catalytic mechanism of Escherichia coli aspartate carbamoyltransferase: A molecular modelling study

J. Eric Gouaux, Kurt L. Krause, William N. Lipscomb

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 293 KB

english, 1987

50

Measurement of Conformational Changes accompanying Desensitization in an Ionotropic Glutamate Receptor

Neali Armstrong, Jaysankar Jasti, Mads Beich-Frandsen, Eric Gouaux

Journal:

Year:

2006

Language:

english

File:

PDF, 769 KB

english, 2006

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